Hair Filler with bioactive peptides is a minimally invasive treatment for hair rejuvenation to increase the density and thickness of hair, available at Institute Medical Laser in Madrid.
Hair Filler is a capillary rejuvenation treatment that increases hair density and thickness
Hair Filler is a preparation composed of hyaluronic acid and 7 types of biomimetic peptides that infiltrate the scalp with a triple objective:
Hair Filler treatment indications are:
The indications of Hair Filler include, among others, different types of alopecia
Bioactive peptides or biopeptides are molecules composed of a sequence of amino acids linked by peptide bonds which play an important role in the physiological processes of the organism. They are regulated by proteolytic control and serve as biomarkers for specific diagnosis and for therapeutics.
Bioactive peptides can be classified as:
Peptides that act as growth factors influence the expression of certain genes that, in turn, synthesize different proteins, which is accompanied by important structural improvements in the organism.
The IML capillary preparation contains the peptides which act as growth factors. They are multifunctional peptides that stimulate the hair follicle cells on 3 levels:
Peptides that act as growth factors can be of two types:
The bioactive peptides act as growth factors to stimulate the hair follicle
The Hair Filler applied by IML in alopecia treatments is a latest generation biopeptide compound formulated with hyaluronic acid.
This injectable is designed to revitalize the follicular cells. The 7 biopeptides comprising Hair Filler influence all the components related to the quality and quantity of hair. These molecules act as growth factors, activating protein signalling pathways and the expression of the genes responsible for the hair revitalization.
Hair Filler acts on the following structures:
Benefits of comprehensive capillary rejuvenation treatment
Hair Filler obtains the following benefits:
Application of Hair Filler treatment should only be conducted by physicians who have received specific training for this injectable.
Under strict aseptic conditions are micro punctures are performed with a 30G needle. The preparation infiltrates through the linear technique to the whole area of the scalp which is being treated.
The micro punctures are performed every 0.2 or 0.3 cm horizontally and every 1 cm vertically.
The amount of product infiltrated for each point is between 0.02 and 0.05 ml.
Once infiltrated, the IML physician performs a gentle massage on the treated area to optimise the homogeneous distribution of the product.
At IML, the average number of sessions of Hair Filler is usually 4, although this number varies according to the needs and goals of each patient. A resting period of a fortnight is required between sessions.
Our physicians recommend applying a monthly maintenance session during the 4 months following treatment.
Hair Filler is compatible with other hair therapies, such as Rigenera stem cell bio-stimulator treatment, plasma rich platelets (PRP) or conventional hair mesotherapy.
Infiltration of the Hair Filler is performed via micro punctures on the scalp
The 7 types of Hair Filler biopeptides are:
Each type or group of biopeptides acts differently in hair rejuvenation:
Acts on the signalling pathways of pluripotent stem cells on the follicular matrix protein. Stimulates dermal papilla, releasing growth factors to the extracellular matrix to start the cycle of follicular growth.
Acts on the protein signalling pathway that influences activation of the follicular cells of the dermal papilla, producing an elongation of the anagen follicular growth stage, the stage in which the hair grows in length. Also by stimulating the growth of new hair shafts.
The benefits of the action of these two biopeptides are:
Stimulates angiogenesis, or new blood vessel formation, by improving microcirculation and, consequently, improving vascularisation of the scalp treated.
In addition, it blocks the DHT expression or Dehydroepiandrosterone, a key molecule in the origin of androgenic alopecia.
These biopeptides stimulate the production of proteins in the follicular cells, facilitating the production of substances that provide the medium suitable for hair regeneration, to produce an increase in hyaluronic acid, keratin and fibronectin fibres synthesis.
They also activate the growth factor that induces the migration and proliferation of follicular cells to form the hair shaft, resulting in highly resistant keratin.
They improve the inter cellular junction of cells that make up the hair shaft, bringing more density and strength to the hair. They also repair damaged cells.
As a result of these stimulations, the following benefits occur:
This biopeptide silences the activity of the genes responsible for the androgenic hair loss by blocking the expression of the gene sensitive to DHT.
In addition, it stimulates the metabolism of melanocytes and their migration, improving the generation of follicular melanin and thus acting on the hair colour.
Degrades the IKB factor, a hair growth inhibiting factor and its subsequent fall causing component.
Promotes gene expression that activates the follicular cycle of hair growth.
Interact on specific receptors in the cell membrane of the hair follicle cells that are involved in the immune response to stimuli, stress and antigens.
The result of the action of these two biopeptides are:
The greater amount of hyaluronic acid present in the scalp induces an improvement in hydration and viscoelasticity in the cell matrix, which improves the metabolism of follicular fibroblasts and, therefore, the elasticity of the hair improved.
Depending on the type of alopecia or the degree of capillary ageing of each patient, our dermatologists can prescribe different combinations of treatments, all of them compatible each other.
Would you like to know whether Hair Filler is for you? Request a free informative consultation now with one of our expert physicians.